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Friday, May 1, 2020 | History

1 edition of Comparative pathophysiology and toxicology of cyclooxygenases found in the catalog.

Comparative pathophysiology and toxicology of cyclooxygenases

Zaher A. Radi

Comparative pathophysiology and toxicology of cyclooxygenases

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  • 3 Currently reading

Published by Wiley in Hoboken, N.J .
Written in English

    Subjects:
  • Pathophysiology,
  • Toxicology,
  • Cyclooxygenases

  • Edition Notes

    Includes Bibliographical references and index.

    StatementZaher A. Radi
    Classifications
    LC ClassificationsRM405.5 .R33 2012
    The Physical Object
    Paginationp. cm.
    ID Numbers
    Open LibraryOL25237395M
    ISBN 109780470577547
    LC Control Number2012002908


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Comparative pathophysiology and toxicology of cyclooxygenases by Zaher A. Radi Download PDF EPUB FB2

Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited. The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as an historical perspective.

Comparative Pathophysiology and Toxicology of Cyclooxygenases: Medicine & Health Science Books @ Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited.

The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as an historical : Wiley. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited.

Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited.

The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as an historical perspective. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited.

The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as. The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases (COXs) are enzymes responsible for the formation of an important class of biological mediators called prostanoids.

Prostanoids such as prostaglandins mediate inflammatory and anaphylactic reactions. For those suffering from inflammation and pain, the. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity Author: Zaher Radi.

A toxicological anatomic pathologist for an international drug company, Radi examines cyclooxygenases (COX) in order to fill a gap in the pathophysiology and toxicology of prostanoids.

COX catalyze the conversion of arachidonic acid into prostaglandins, he explains, which play a significant role in the health and disease of many organ systems, and these systems are the.

Comparative Physiological, Developmental, and Anatomical Aspects of the Renal System. Role of Prostaglandins in the Renal System. COX‐1 and COX‐2 Expression in the Kidney. Effects of ns‐NSAIDs on the Kidney. Effects of COX‐2 s‐NSAIDs on the Kidney.

Potential Mechanisms of NSAID Effects on the Renal System. Conclusions. References. The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Cyclooxygenases (COXs) are enzymes.

Yet the use of NSAIDs can trigger toxicological effects as well, leading to potential health risks. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides a comprehensive overview of how COX inhibitors affect various bodily systems, specifically the toxicity mechanisms triggered when the COX enzyme is inhibited.

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Lee "Comparative Pathophysiology and Toxicology of Cyclooxygenases" por Zaher A. Radi disponible en Rakuten Kobo. The first thorough review of cyclooxygenase inhibitors, including their toxicity mechanisms and toxicopathological risks Brand: Wiley.

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Request PDF | Introduction: Discovery of Cyclooxygenases and Historical Perspective | Aspirin Prostaglandins Cyclooxygenases COX-2 Selective NSAIDs References | Find, read and cite all the. The book provides an introduction to the discovery of cyclooxygenases, their use as therapeutic agents, as well as an historical perspective.

Shedding light on the differences in expression, pathophysiology, and toxicology of COX inhibitors across species, the book offers a systematic examination of the effects and pathophysiology of COX.

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Comparative pathophysiology and toxicology of cyclooxygenases By Radi, Zaher A. eBook. English. Comparative Pathophysiology and Toxicology of Cyclooxygenases provides on the differences in expression, pathophysiology, and toxicology of COX inhibitors ISBN: Follow Zaher A.

Radi and explore their bibliography from 's Zaher A. Radi Author Page. (John Wiley & Sons (Books)) Ciba Foundation Symposium 76 - Environmental Chemicals, Enzyme Function and Human Disease / Evered.

(John Wiley & Sons (Books)) Cigarette Smoke Toxicity - Linking Individual Chemicals to Human Diseases / Bernhard. (John Wiley & Sons (Books)) Clinical Toxicology Taylor & Francis v. 1 () - current issue. Pathophysiology of cyclooxygenases in cardiovascular homeostasis. Sellers RS(1), Radi ZA, Khan NK.

Author information: (1)Albert Einstein College of Medicine Cancer Center, Histology and Comparative Pathology Facility, Price Center, Morris Park Ave, Bronx, NYUSA. [email protected] by: 1. Author(s): Radi,Zaher A Title(s): Comparative pathophysiology and toxicology of cyclooxygenases/ Zaher A.

Radi. Country of Publication: United States Publisher. Purchase Haschek and Rousseaux's Handbook of Toxicologic Pathology - 2nd Edition.

Print Book & E-Book. ISBNGeneral Pathology Lecture Notes For Health Science Students. This book is intended to be a textbook of general pathology for health science students. General pathology covers the basic mechanisms of diseases whereas systemic pathology covers diseases as they occur in each organ system.

This book covers only general pathology. Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals.

The current edition also includes comparative. Comparative pathophysiology and toxicology of cyclooxygenases () Oxidative stress in vertebrates and invertebrates () Cell-tissue injury and cytoprotection-organoprotection in the gastrointestinal tract ().

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Product Type: Book Edition: 1 First Published: Paperback: COX is currently believed to exist in three isoforms (see Table 1).Cyclooxygenase-1 (COX-1), first cloned inis located on chromosome 9 and is constitutively expressed in most tissues (Merlie et al., ).COX-1 is a housekeeping enzyme responsible for various physiological functions, and plays a critical role in protection of gastric mucosa, platelet aggregation, renal blood flow, and Cited by: Harborne – poilmeros pages Comparative electrophoretic studies on mammalian plasma proteins by George Emerson Riley – – pages Comparative enzymology of two glycerolphosphate dehydrogenase isozymes from chicken by Harold Bancroft White – – pages Comparative Pathophysiology and Toxicology of Cyclooxygenases by Zaher A.

Coffee Flavor. Harborne – – pages Comparative electrophoretic studies on mammalian plasma proteins by George Emerson Riley – – pages Comparative enzymology of two glycerolphosphate dehydrogenase isozymes from chicken by Harold Bancroft White – – pages Comparative Pathophysiology and Toxicology of Cyclooxygenases by Zaher A.

Direct evidence of the cyclooxygenase pathway of prostaglandin synthesis in arthropods: Genetic and biochemical characterization of two crustacean cyclooxygenases.

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For Researchers For Publishers For Librarians For Educators/Trainers For Healthcare Professionals For the Public. LocatorPlus is the Library's online catalog containing catalog records for books, audiovisuals, journals, computer files, and other materials in the Library's collections.

Toxicology and Environmental Health. Wiley also publishes its books in a variety of electr onic formats. Some content that appears in print, however, may not be available in electronic format.

Library of Congress Cataloging-in-Publication Data: Hodgson, Ernest, Ð A textbook of modern toxicology / Ernest Hodgson.Ñ3rd ed. Includes bibliographical references and index. Comparative pathophysiology and toxicology of cyclooxygenases Resveratrol was found to act as an antioxidant and antimutagen and to induce phase II drug-metabolizing enzymes (anti-initiation activity); it mediated anti-inflammatory effects and inhibited cyclooxygenase and hydroperoxidase functions (antipromotion activity); and it induced human.

RADI is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms. Radi examines cyclooxygenases (COX) in order to fill a gap in the pathophysiology and toxicology of prostanoids.

Comparative pathophysiology and toxicology of cyclooxygenases. Perth, Australia, J .New Aspects in Molecular and Cellular Mechanisms of Human Carcinogenesis. Edited by Written by an international team of experts in the field of human carcinogenesis, this book discusses recent advances in cancer research, which include the following topics: basic molecular and cellular mechanisms behind cancer growth, new approaches in cancer therapy, and cancer diagnostic.This paper provides a review of the comparative expression of COX-1 and COX-2 in the eye under normal and pathologic conditions, including the pathophysiologic role of PGs, and the effects of ns-NSAIDs and selective COX-2 inhibitors in the treatment of ophthalmic by: